diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index b94257eae2..0bcf3ae75d 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -13713,14 +13713,14 @@ (define-public r-monocle3
 (define-public r-noiseq
   (package
     (name "r-noiseq")
-    (version "2.44.0")
+    (version "2.46.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "NOISeq" version))
        (sha256
         (base32
-         "0cxhy4yrww6bh4z603389fikhix8rhfy04ylhm74fdmdng4jblg6"))))
+         "0qs0sc47n3p9wmf5cmc39cb30i8pbsyizhr29b3ld197pi1ba5wb"))))
     (properties `((upstream-name . "NOISeq")))
     (build-system r-build-system)
     (propagated-inputs