diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 739b87cfca..a963249adf 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -13622,14 +13622,14 @@ (define-public r-zfpkm
 (define-public r-rbowtie2
   (package
     (name "r-rbowtie2")
-    (version "2.4.0")
+    (version "2.4.2")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rbowtie2" version))
        (sha256
         (base32
-         "05cczwkhv7kfnhlr0qznk6vdjncaj907895923f8mwx4j4cy5gcz"))))
+         "0cbm6q4v9ddyx4gnw2p47ssyhnmjfxahvzbzwjzn0my3ixssy0aj"))))
     (properties `((upstream-name . "Rbowtie2")))
     (build-system r-build-system)
     (propagated-inputs