diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 4d070b093c..74761c0464 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -1964,13 +1964,13 @@ (define-public jellyfish
 (define-public macs
   (package
     (name "macs")
-    (version "2.1.0.20140616")
+    (version "2.1.0.20151222")
     (source (origin
               (method url-fetch)
               (uri (pypi-uri "MACS2" version))
               (sha256
                (base32
-                "11lmiw6avqhwn75sn59g4lfkrr2kk20r3rgfbx9xfqb8rg9mi2n6"))))
+                "1r2hcz6irhcq7lwbafjks98jbn34hv05avgbdjnp6w6mlfjkf8x5"))))
     (build-system python-build-system)
     (arguments
      `(#:python ,python-2 ; only compatible with Python 2.7