diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index ffa3ba7133..cb3b61e57b 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -8581,13 +8581,13 @@ (define-public r-hpar
 (define-public r-r3cseq
   (package
     (name "r-r3cseq")
-    (version "1.48.0")
+    (version "1.50.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "r3Cseq" version))
        (sha256
-        (base32 "1llkfcy13h0c973703jmpgp2n6xxfsizb9iw1wxzgkbp1v0iy268"))))
+        (base32 "02dc6milwymwj90x24fip8av84ik9dp69sg9g7l300kwyk0hcrb7"))))
     (properties `((upstream-name . "r3Cseq")))
     (build-system r-build-system)
     (propagated-inputs