diff --git a/guix/build/gnu-build-system.scm b/guix/build/gnu-build-system.scm
index 09f272edee..e37b751403 100644
--- a/guix/build/gnu-build-system.scm
+++ b/guix/build/gnu-build-system.scm
@@ -39,6 +39,13 @@ (define-module (guix build gnu-build-system)
 ;;
 ;; Code:
 
+(cond-expand
+  (guile-2.2
+   ;; Guile 2.2.2 has a bug whereby 'time-monotonic' objects have seconds and
+   ;; nanoseconds swapped (fixed in Guile commit 886ac3e).  Work around it.
+   (define time-monotonic time-tai))
+  (else #t))
+
 (define* (set-SOURCE-DATE-EPOCH #:rest _)
   "Set the 'SOURCE_DATE_EPOCH' environment variable.  This is used by tools
 that incorporate timestamps as a way to tell them to use a fixed timestamp.