diff --git a/gnu/packages/emulators.scm b/gnu/packages/emulators.scm
index 3695311c87..84441181c7 100644
--- a/gnu/packages/emulators.scm
+++ b/gnu/packages/emulators.scm
@@ -1520,6 +1520,10 @@ (define-public retroarch
                  (("/usr/local/share/wayland-protocols")
                  (string-append wayland-protocols "/share/wayland-protocols")))
 
+               ;; Without HLSL, we can still enable GLSLANG and Vulkan support.
+               (substitute* "qb/config.libs.sh"
+                 (("[$]HAVE_GLSLANG_HLSL") "notcare"))
+
                ;; The configure script does not yet accept the extra arguments
                ;; (like ‘CONFIG_SHELL=’) passed by the default configure phase.
                (invoke