diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 37483984ec..965e26b812 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -7554,7 +7554,7 @@ (define-public prinseq
          (delete 'configure)
          (delete 'build)
          (replace 'install
-           (lambda* (#:key outputs #:allow-other-keys)
+           (lambda* (#:key inputs outputs #:allow-other-keys)
              (let* ((out (assoc-ref outputs "out"))
                     (bin (string-append out "/bin"))
                     (scripts (find-files "." "prinseq.*.pl"))
@@ -10239,6 +10239,7 @@ (define-public gess
 " line)))
                ;; Make sure GESS has all modules in its path
                (wrap-script (string-append target "GESS.py")
+                 #:guile (search-input-file inputs "bin/guile")
                  `("GUIX_PYTHONPATH" ":" = (,target ,(getenv "GUIX_PYTHONPATH"))))
                (mkdir-p bin)
                (symlink (string-append target "GESS.py")