diff --git a/etc/guix-install.sh b/etc/guix-install.sh
index e7f4d2cd59..d7fde7aacd 100755
--- a/etc/guix-install.sh
+++ b/etc/guix-install.sh
@@ -414,7 +414,9 @@ if [ -L $_GUIX_PROFILE ]; then
   export PATH="$_GUIX_PROFILE/bin${PATH:+:}$PATH"
   # Export INFOPATH so that the updated info pages can be found
   # and read by both /usr/bin/info and/or $GUIX_PROFILE/bin/info
-  export INFOPATH="$_GUIX_PROFILE/share/info${INFOPATH:+:}$INFOPATH"
+  # When INFOPATH is unset, add a trailing colon so that Emacs
+  # searches 'Info-default-directory-list'.
+  export INFOPATH="$_GUIX_PROFILE/share/info:$INFOPATH"
 fi
 
 # GUIX_PROFILE: User's default profile