diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index a55b7bc4a4..f45f2ff08a 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -2685,13 +2685,13 @@ (define-public r-amountain
 (define-public r-amplican
   (package
     (name "r-amplican")
-    (version "1.20.0")
+    (version "1.21.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "amplican" version))
               (sha256
                (base32
-                "1c990i6gxbarcpbdpkz017x94spwzap95l95synlizbkyif4z8ij"))))
+                "0y8x3vfsa2330zabd2y3f6ipi1f5zlfn9pp0cg2rks0pfnx2qqha"))))
     (properties `((upstream-name . "amplican")))
     (build-system r-build-system)
     (propagated-inputs