diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index d28b671b8b..18629deb44 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -906,14 +906,14 @@ (define-public r-hpar
 (define-public r-regioner
   (package
     (name "r-regioner")
-    (version "1.14.0")
+    (version "1.16.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "regioneR" version))
        (sha256
         (base32
-         "19la74swgzxp90z2nr3pzsgkxd7wp70zl6i2ipv3plg841f6k5zd"))))
+         "014h2q346ynfdbpavh4p69cyv4j65hk934liq5892zznjzl73z7p"))))
     (properties `((upstream-name . "regioneR")))
     (build-system r-build-system)
     (propagated-inputs