diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 95ef8ca193..b5bc0f0aa2 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -12357,14 +12357,14 @@ (define-public r-fourcseq
 (define-public r-preprocesscore
   (package
     (name "r-preprocesscore")
-    (version "1.54.0")
+    (version "1.56.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "preprocessCore" version))
        (sha256
         (base32
-         "17a00blz4kvhmsk92bp5alj9kdpy7h1id7nk4vqxakhkb2jabr20"))))
+         "1i93vdqa6pwzamiryp3lv6cyvhx9shs01is0q6vbmdvcbii2vf3x"))))
     (properties
      `((upstream-name . "preprocessCore")))
     (build-system r-build-system)