diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index e8e6e9dfba..bc67b27d6c 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -5903,7 +5903,7 @@ (define-public seek
 (define-public samtools
   (package
     (name "samtools")
-    (version "1.11")
+    (version "1.12")
     (source
      (origin
        (method url-fetch)
@@ -5912,11 +5912,11 @@ (define-public samtools
                        version "/samtools-" version ".tar.bz2"))
        (sha256
         (base32
-         "1dp5wknak4arnw5ghhif9mmljlfnw5bgm91wib7z0j8wdjywx0z2"))
+         "1jrdj2idpma5ja9cg0rr73b565vdbr9wyy6zig54bidicc2pg8vd"))
        (modules '((guix build utils)))
        (snippet '(begin
                    ;; Delete bundled htslib.
-                   (delete-file-recursively "htslib-1.11")
+                   (delete-file-recursively "htslib-1.12")
                    #t))))
     (build-system gnu-build-system)
     (arguments