diff --git a/gnu/packages/ruby.scm b/gnu/packages/ruby.scm
index 7ea88b4067..1bf2db17cc 100644
--- a/gnu/packages/ruby.scm
+++ b/gnu/packages/ruby.scm
@@ -11572,6 +11572,12 @@ (define-public ruby-puma
             (lambda* (#:key tests? #:allow-other-keys)
               (when tests?
                 (invoke "bundle" "exec" "rake" "test"))))
+          (add-after 'install 'delete-mkmf.log
+            (lambda _
+              ;; Rubygems installs build log files that embed volatile file
+              ;; names (see:
+              ;; https://github.com/rubygems/rubygems/issues/6259).
+              (for-each delete-file (find-files #$output "^mkmf\\.log$"))))
           (add-before 'check 'disable-problematic-tests
             (lambda _
               (let-syntax ((skip-tests