diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 00840ca124..a66cc22fff 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -12401,13 +12401,13 @@ (define-public r-preprocesscore
 (define-public r-s4vectors
   (package
     (name "r-s4vectors")
-    (version "0.32.2")
+    (version "0.32.3")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "S4Vectors" version))
               (sha256
                (base32
-                "0xrmii2dnwyknpjdiwwjlklgzpbk9q09br27rq5ffz08if9yyk20"))))
+                "0wp29v41f9cf6khq2ww0f63nsq6219l1ycajzdqp3a2xda734ncw"))))
     (properties
      `((upstream-name . "S4Vectors")))
     (build-system r-build-system)