diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index a7555ce6b1..96559748ce 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -6254,14 +6254,14 @@ (define-public r-annotationforge
 (define-public r-annotationhub
   (package
     (name "r-annotationhub")
-    (version "3.8.0")
+    (version "3.10.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "AnnotationHub" version))
        (sha256
         (base32
-         "0ri8qj5j10bhprkb810c2hl5sl944kpb8rf5lab6nxykzgyz73v0"))))
+         "1mx3vip1rx5lq0vnkxpmkyksnq4vygmww85vxq3spr0fah1pwnkr"))))
     (properties `((upstream-name . "AnnotationHub")))
     (build-system r-build-system)
     (propagated-inputs