diff --git a/gnu/packages/python-xyz.scm b/gnu/packages/python-xyz.scm
index 9f00dbc889..6b2e233165 100644
--- a/gnu/packages/python-xyz.scm
+++ b/gnu/packages/python-xyz.scm
@@ -21403,35 +21403,6 @@ (define-public python-pyro4
 objects on other machines, also known as remote procedure calls (RPC).")
     (license license:expat)))
 
-(define-public python2-pyro
-  (package
-    (name "python2-pyro")
-    (version "3.16")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (pypi-uri "Pyro" version))
-       (file-name (string-append "Pyro-" version ".tar.gz"))
-       (sha256
-        (base32
-         "0y75wzdqbjy565rpxaxscav4j8xg060sa90lnmb7aypgaf251v8v"))))
-    (build-system python-build-system)
-    (arguments
-     ;; Pyro is not compatible with Python 3
-     `(#:python ,python-2
-       ;; Pyro has no test cases for automatic execution
-       #:tests? #f))
-    (home-page "https://pythonhosted.org/Pyro/")
-    (synopsis "Distributed object manager for Python")
-    (description "Pyro is a Distributed Object Technology system
-written in Python that is designed to be easy to use.  It resembles
-Java's Remote Method Invocation (RMI).  It has less similarity to CORBA,
-which is a system and language independent Distributed Object Technology
-and has much more to offer than Pyro or RMI.  Pyro 3.x is no
-longer maintained.  New projects should use Pyro4 instead, which
-is the new Pyro version that is actively developed.")
-    (license license:expat)))
-
 (define-public python-phonenumbers
   (package
     (name "python-phonenumbers")