diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 49aa230877..b41de4730e 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -10393,14 +10393,14 @@ (define-public r-sgseq
 (define-public r-rhisat2
   (package
     (name "r-rhisat2")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "Rhisat2" version))
        (sha256
         (base32
-         "092rws9vjxgm2jpkbp6ign47zmillyyidnc7ylcbn4zr9j5lwv0y"))))
+         "0hzair41l47kzykymd169a34pfhb98vrjgkgdf15m17csyz7pnv7"))))
     (properties `((upstream-name . "Rhisat2")))
     (build-system r-build-system)
     (arguments