diff --git a/gnu/packages/multiprecision.scm b/gnu/packages/multiprecision.scm
index 9ae79afed9..2ea87f8e12 100644
--- a/gnu/packages/multiprecision.scm
+++ b/gnu/packages/multiprecision.scm
@@ -123,13 +123,13 @@ (define-public gmp-6.0
 (define-public mpfr
   (package
    (name "mpfr")
-   (version "4.2.0")
+   (version "4.2.1")
    (source (origin
             (method url-fetch)
             (uri (string-append "mirror://gnu/mpfr/mpfr-" version
                                 ".tar.xz"))
             (sha256 (base32
-                     "14yr4sf4mys64nzbgnd997l6l4n8l9vsjnnvnb0lh4jh2ggpi8q6"))))
+                     "1cnb3y7y351qg6r7ynwsgaykm7l2a8zg2nlljs4rf9k778shfy17"))))
    (arguments
     (list
      #:phases (if (system-hurd?)