diff --git a/gnu/packages/python-science.scm b/gnu/packages/python-science.scm
index ea2b8236d5..2650ac46d6 100644
--- a/gnu/packages/python-science.scm
+++ b/gnu/packages/python-science.scm
@@ -473,6 +473,8 @@ (define-public python-scikit-image
     (build-system pyproject-build-system)
     (arguments
      (list
+      ;; Disable flaky test
+      #:test-flags #~(list "-k" "not test_ellipse_parameter_stability")
       #:phases
       #~(modify-phases %standard-phases
           (add-before 'build 'change-home-dir