diff --git a/gnu/local.mk b/gnu/local.mk
index 35b9dc0406..5442edea7a 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1067,6 +1067,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/clang-cling-13-libc-search-path.patch	\
   %D%/packages/patches/clang-runtime-asan-build-fixes.patch	\
   %D%/packages/patches/clang-runtime-esan-build-fixes.patch	\
+  %D%/packages/patches/clang-runtime-13-glibc-2.36-compat.patch	\
   %D%/packages/patches/clang-runtime-14-glibc-2.36-compat.patch	\
   %D%/packages/patches/clang-runtime-9-libsanitizer-mode-field.patch	\
   %D%/packages/patches/clang-runtime-3.5-libsanitizer-mode-field.patch	\
diff --git a/gnu/packages/llvm.scm b/gnu/packages/llvm.scm
index 71ceb4e44f..34bf125695 100644
--- a/gnu/packages/llvm.scm
+++ b/gnu/packages/llvm.scm
@@ -813,7 +813,8 @@ (define-public llvm-13
 (define-public clang-runtime-13
   (clang-runtime-from-llvm
    llvm-13
-   "1z2xr9nn4mgc3hn9ark2k5y4wznpk47xppkp63bcbagr6589acvv"))
+   "1z2xr9nn4mgc3hn9ark2k5y4wznpk47xppkp63bcbagr6589acvv"
+   '("clang-runtime-13-glibc-2.36-compat.patch")))
 
 (define-public clang-13
   (clang-from-llvm llvm-13 clang-runtime-13
diff --git a/gnu/packages/patches/clang-runtime-13-glibc-2.36-compat.patch b/gnu/packages/patches/clang-runtime-13-glibc-2.36-compat.patch
new file mode 100644
index 0000000000..e457713d16
--- /dev/null
+++ b/gnu/packages/patches/clang-runtime-13-glibc-2.36-compat.patch
@@ -0,0 +1,50 @@
+This commit is from upstream and is included in the llvm-15 release
+
+commit b379129c4beb3f26223288627a1291739f33af02
+Author: Fangrui Song <i@maskray.me>
+Date:   Mon Jul 11 11:38:28 2022 -0700
+
+    [sanitizer] Remove #include <linux/fs.h> to resolve fsconfig_command/mount_attr conflict with glibc 2.36
+    
+    It is generally not a good idea to mix usage of glibc headers and Linux UAPI
+    headers (https://sourceware.org/glibc/wiki/Synchronizing_Headers). In glibc
+    since 7eae6a91e9b1670330c9f15730082c91c0b1d570 (milestone: 2.36), sys/mount.h
+    defines `fsconfig_command` which conflicts with linux/mount.h:
+    
+        .../usr/include/linux/mount.h:95:6: error: redeclaration of ‘enum fsconfig_command’
+    
+    Remove #include <linux/fs.h> which pulls in linux/mount.h. Expand its 4 macros manually.
+    
+    Fix https://github.com/llvm/llvm-project/issues/56421
+    
+    Reviewed By: #sanitizers, vitalybuka, zatrazz
+    
+    Differential Revision: https://reviews.llvm.org/D129471
+
+diff --git a/lib/sanitizer_common/sanitizer_platform_limits_posix.cpp b/lib/sanitizer_common/sanitizer_platform_limits_posix.cpp
+index 4bd425435d56..81740bf4ab39 100644
+--- a/lib/sanitizer_common/sanitizer_platform_limits_posix.cpp
++++ b/lib/sanitizer_common/sanitizer_platform_limits_posix.cpp
+@@ -73,7 +73,6 @@
+ #include <sys/vt.h>
+ #include <linux/cdrom.h>
+ #include <linux/fd.h>
+-#include <linux/fs.h>
+ #include <linux/hdreg.h>
+ #include <linux/input.h>
+ #include <linux/ioctl.h>
+@@ -876,10 +875,10 @@ unsigned struct_ElfW_Phdr_sz = sizeof(Elf_Phdr);
+   unsigned IOCTL_EVIOCGPROP = IOCTL_NOT_PRESENT;
+   unsigned IOCTL_EVIOCSKEYCODE_V2 = IOCTL_NOT_PRESENT;
+ #endif
+-  unsigned IOCTL_FS_IOC_GETFLAGS = FS_IOC_GETFLAGS;
+-  unsigned IOCTL_FS_IOC_GETVERSION = FS_IOC_GETVERSION;
+-  unsigned IOCTL_FS_IOC_SETFLAGS = FS_IOC_SETFLAGS;
+-  unsigned IOCTL_FS_IOC_SETVERSION = FS_IOC_SETVERSION;
++  unsigned IOCTL_FS_IOC_GETFLAGS = _IOR('f', 1, long);
++  unsigned IOCTL_FS_IOC_GETVERSION = _IOR('v', 1, long);
++  unsigned IOCTL_FS_IOC_SETFLAGS = _IOW('f', 2, long);
++  unsigned IOCTL_FS_IOC_SETVERSION = _IOW('v', 2, long);
+   unsigned IOCTL_GIO_CMAP = GIO_CMAP;
+   unsigned IOCTL_GIO_FONT = GIO_FONT;
+   unsigned IOCTL_GIO_UNIMAP = GIO_UNIMAP;