diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 9e7191dad8..39f4a20051 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -11061,6 +11061,9 @@ (define-public pigx-bsseq
          (add-before 'bootstrap 'autoreconf
            (lambda _
              (invoke "autoreconf" "-vif")))
+         (add-before 'configure 'set-PYTHONPATH
+           (lambda _
+             (setenv "PYTHONPATH" (getenv "GUIX_PYTHONPATH"))))
          (add-before 'check 'set-timezone
            ;; The readr package is picky about timezones.
            (lambda* (#:key inputs #:allow-other-keys)